Curtin Logo Colour current research text box

Daniel Brown CurtinPrincipal Investigator: Dr. Daniel Brown  

Disease: Menière’s disease

Research Description: Menière’s disease (MD) is a hearing and balance disorder with no known cause, although MD is believed to involve dysfunction of a structure in the inner ear called the endolymphatic sac (ES), located deep in the skull. While steroids injected into the middle ear is a current method used to treat MD, the steroids do not penetrate deep into the inner ear or reach the ES, which may limit the success of this treatment. Interestingly, an old therapy for MD involves ingesting a diuretic such as glycerol, and preliminary data suggests that glycerol may aid steroid absorption into the ES. This phenomenon offers the potential for therapeutic drugs to be better absorbed into the ES if delivered with oral glycerol. Dr. Brown’s team will use an animal model to validate and optimize a method for delivering steroids, in combination with glycerol, to the ES. Results from this study could be used as proof of concept for a new technique to deliver steroids to the inner ear more effectively, leading to a new avenue of research and possibly treatment.

 

CWR funding role: Primary funder

CWR funding parter: Becky and Lester Knight

 

Click here to sign up for our eNewsletter today!

Please include your Full Name* and Email Address*

*required

If the link above doesn't work, please contact our Admin support at admin@cureswithinreach.org with your Full Name and Email Address to sign up!

 

Cures Within Reach

134 N. LaSalle, #1130
Chicago, IL 60602

info@cureswithinreach.org

All funds donated to Cures Within Reach may be tax deductible for federal income tax purposes. 

Partnership for Cures DBA Cures Within Reach is recognized by the IRS as a 501(c)3 tax-exempt not-for-profit organization, tax ID 20-3620169.

 

Monday the 25th. Copyright 2018 Cures Within Reach.